Researchers from the University of Iowa, Caver College of Medicine have published a new study linking multiple sclerosis (MS) to gut bacteria.
Different gut bacteria populations have been linked to different chronic diseases. MS is one of the latest immune disorders to be linked.
“Every human carries trillions of bacteria in their gut (gut microbiome) and recent advances in research indicate that these tiny passengers play an important role in our overall health maintenance,” says Ashutosh Mangalam, PhD, assistant professor of pathology at the University of Iowa Carver College of Medicine.
The study, published online in the Scientific Reports journal, identified that MS patients have a distinct microbiome from their healthy peers. A microbiome analysis of fecal samples collected from MS patients as well has healthy control subjects was conducted.
“Although preliminary, our data suggest that patients with MS have reduced levels of good bacteria responsible for overall benefits obtained from consuming healthy foods, such as soybean and flaxseeds,” says Mangalam, who is senior author on the study.
“We identified certain bacteria which are increased or decreased in the gut of patients with MS compared to healthy controls,” he said.
Jun Chen, Nicholas Chia, Krishna R. Kalari, Janet Z. Yao, Martina Novotna, M. Mateo Paz Soldan, David H. Luckey, Eric V. Marietta, Patricio R. Jeraldo, Xianfeng Chen, Brian G. Weinshenker, Moses Rodriguez, Orhun H. Kantarci, Heidi Nelson, Joseph A. Murray, Ashutosh K. Mangalam. Multiple sclerosis patients have a distinct gut microbiota compared to healthy controls. Scientific Reports, 2016; 6: 28484 DOI: 10.1038/srep28484